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Defective regulation of the eIF2-eIF2B translational axis underlies depressive-like behavior in mice and correlates with major depressive disorder in humans
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Effect of psilocybin versus escitalopram on depression symptom severity in patients with moderate-to-severe major depressive disorder: observational 6-month follow-up of a phase 2, double-blind, randomised, controlled trial
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Increasing hexokinase 1 expression improves mitochondrial and glycolytic functional deficits seen in sporadic Alzheimer’s disease astrocytes
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Frontostriatal salience network expansion in individuals in depression
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Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
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A therapeutic small molecule enhances γ-oscillationsand improves cognition/memory in Alzheimer’s disease model mice
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Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes
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Psilocybin desynchronizes the human brain
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Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions
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A cognitive neural circuit biotype of depression showing functional and behavioral improvement after transcranial magnetic stimulation in the B-SMART-fMRI trial
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Serotonergic psychedelic 5-MeO-DMT alters plasticity-related gene expression and generates anxiolytic effects in stressed mice
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AI-based differential diagnosis of dementia etiologies on multimodal data
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Nasal tau immunotherapy clears intracellular tau pathology and improves cognitive functions in aged tauopathy mice
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Altering heparan sulfate suppresses cell abnormalities and neuron loss in Drosophila presenilin model of Alzheimer Disease
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The microtubule-dynamin binding inhibitor peptide PHDP5 rescues spatial learning and memory deficits in Alzheimer’s disease model mice
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TERT activation targets DNA methylation and multiple aging hallmarks
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Stress-resilience impacts psychological wellbeing as evidenced by brain–gut microbiome interactions
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Gliovascular transcriptional perturbations in Alzheimer’s disease reveal molecular mechanisms of blood brain barrier dysfunction
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Personalized brain circuit scores identify clinically distinct biotypes in depression and anxiety
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Bidirectional Associations of Depressive Symptoms and Cognitive Function Over Time
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The metabolome-wide signature of major depressive disorder
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Effects of SPI1-mediated transcriptome remodeling on Alzheimer’s disease-related phenotypes in mouse models of Aβ amyloidosis
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Structural pharmacology and therapeutic potential of 5-methoxytryptamines
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Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer’s disease
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Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β
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Key variants via the Alzheimers Disease Sequencing Project whole genome sequence data
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Scanning ultrasound-mediated memory and functional improvements do not require amyloid-β reduction
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APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia
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Multisensory gamma stimulation promotes glymphatic clearance of amyloid
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(R)-ketamine restores anterior insular cortex activity and cognitive deficits in social isolation-reared mice