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Phospho-tau serine-262 and serine-356 as biomarkers of pre-tangle soluble tau assemblies in Alzheimer’s disease
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Massive changes in gene expression and their cause(s) can be a unifying principle in the pathobiology of Alzheimers disease
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Pancreatic β cell-secreted factor FGF23 attenuates Alzheimers disease-related amyloid β-induced neuronal death
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Unusual Phospholipids from Morganella morganii Linked to Depression
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Inhaled xenon modulates microglia and ameliorates disease in mouse models of amyloidosis and tauopathy
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Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies
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Biophysical mapping of TREM2-ligand interactions reveals shared surfaces for engagement of multiple Alzheimer’s disease ligands
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Modulation of glymphatic system by visual circuit activation alleviates memory impairment and apathy in a mouse model of Alzheimer’s disease
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Brain-wide cell-type-specific transcriptomic signatures of healthy ageing in mice
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Psilocybin increases emotional empathy in patients with major depression
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Ketamine induces plasticity in a norepinephrine-astroglial circuit to promote behavioral perseverance
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Aged neurons don’t register energy need
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Genome-wide methylome-based molecular pathologies associated with depression and suicide
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Formation of long-term memory without short-term memory revealed by CaMKII inhibition
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Opponent control of reinforcement by striatal dopamine and serotonin
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Gene–dose-dependent reduction of Fshr expression improves spatial memory deficits in Alzheimer’s mice
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Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer’s disease
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TYK2 regulates tau levels, phosphorylation and aggregation in a tauopathy mouse model
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Carbonic anhydrase inhibition ameliorates tau toxicity via enhanced tau secretion
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Defective regulation of the eIF2-eIF2B translational axis underlies depressive-like behavior in mice and correlates with major depressive disorder in humans
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Effect of psilocybin versus escitalopram on depression symptom severity in patients with moderate-to-severe major depressive disorder: observational 6-month follow-up of a phase 2, double-blind, randomised, controlled trial
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Increasing hexokinase 1 expression improves mitochondrial and glycolytic functional deficits seen in sporadic Alzheimer’s disease astrocytes
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Frontostriatal salience network expansion in individuals in depression
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Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
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A therapeutic small molecule enhances γ-oscillationsand improves cognition/memory in Alzheimer’s disease model mice
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Treatment with shRNA to knockdown the 5-HT2A receptor improves memory in vivo and decreases excitability in primary cortical neurons
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Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes
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Psilocybin desynchronizes the human brain
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Ketamine metabolism via hepatic CYP450 isoforms contributes to its sustained antidepressant actions
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Serotonergic psychedelic 5-MeO-DMT alters plasticity-related gene expression and generates anxiolytic effects in stressed mice